Metabolic
5-Amino-1MQ
5-Amino-1MQ is a small molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an enzyme that regulates cellular energy metabolism in adipose tissue. By blocking NNMT, it increases intracellular NAD+ and SAM (S-adenosyl methionine) concentrations, promoting fat cell energy expenditure. Preclinical studies have shown it reduces body weight and adiposity without affecting food intake.
Quick Facts
CategoryMetabolic
Half-life8 hours
Routesoral, subcutaneous
FDA statusNot approved
StorageRoom temperature (15-25°C). Reconstituted: 90 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Conservative Fat Loss | 25 mg | 1x/day | oral | 8 weeks | 25mg daily with food. 8-12 week cycle. |
| Standard Fat Loss | 50 mg | 1x/day | oral | 8 weeks | 50mg daily with food. Standard starting dose. 8-12 week cycle. |
| Typical Maintenance | 75 mg | 1x/day | oral | 8 weeks | 75mg daily with food. 8-12 week cycle. |
| Maximum Dose | 100 mg | 1x/day | oral | 8 weeks | 100mg daily with food. Maximum dose studied. 8-12 week cycle. |
| Split Dosing Protocol | 50 mg | 2x/day | oral | 8 weeks | 50mg twice daily with meals. 8-12 week cycle. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
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Start Tracking — FreeCommon Questions
What is the typical dose of 5-Amino-1MQ?
A common dose for 5-Amino-1MQ is 25 mg 1x/day via oral. 25mg daily with food. 8-12 week cycle.
What is the half-life of 5-Amino-1MQ?
The half-life of 5-Amino-1MQ is approximately 8 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store 5-Amino-1MQ?
Store 5-Amino-1MQ at Room temperature (15-25°C). Oral small molecule, not a peptide. Store in a cool, dry place. Available as capsules; no reconstitution needed. Once reconstituted, use within 90 days.
Is 5-Amino-1MQ FDA approved?
5-Amino-1MQ is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.