Metabolic
AOD-9604
AOD-9604 is a synthetic peptide fragment corresponding to amino acids 177-191 of human growth hormone, with a tyrosine substitution at position 177. It retains the lipolytic (fat-reducing) activity of growth hormone without its growth-promoting or diabetogenic effects. AOD-9604 stimulates lipolysis and inhibits lipogenesis by modulating beta-3 adrenergic receptor pathways in adipose tissue.
Quick Facts
Also known ashGH Fragment 176-191
CategoryMetabolic
Half-life30 minutes
Routessubcutaneous, oral
Common vial sizes2mg, 3mg, 5mg, 10mg
Molecular weight1815.1 Da
Chain length17 amino acids
SequenceTyr-Leu-Arg-Ile-Val-Gln-Cys-Arg-Ser-Val-Glu-Gly-Ser-Cys-Gly-Phe
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Fat Loss | 275 mcg | 1x/day | subcutaneous | 10 weeks | 250-300mcg once daily. 8-12 week cycle. Inject in abdominal area. |
| Enhanced Fat Loss | 450 mcg | 1x/day | subcutaneous | 10 weeks | 400-500mcg once daily. 8-12 week cycle. |
| Joint Support | 250 mcg | 1x/day | subcutaneous | 10 weeks | 250mcg once daily. 8-12 week cycle. |
| Conservative Start | 200 mcg | 1x/day | subcutaneous | 10 weeks | 200mcg once daily. 8-12 week cycle. Conservative starting dose. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your AOD-9604 Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute AOD-9604?
Add bacteriostatic water to your AOD-9604 vial (common sizes: 2mg, 3mg, 5mg, 10mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of AOD-9604?
A common dose for AOD-9604 is 275 mcg 1x/day via subcutaneous. 250-300mcg once daily. 8-12 week cycle. Inject in abdominal area.
What is the half-life of AOD-9604?
The half-life of AOD-9604 is approximately 30 minutes. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store AOD-9604?
Store AOD-9604 at 2-8°C (refrigerated). Also available in oral and transdermal formulations for research. Reconstituted injectable form should be refrigerated. Once reconstituted, use within 21 days.
Is AOD-9604 FDA approved?
AOD-9604 is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
Related Calculators
References
- Metabolic studies of a synthetic lipolytic domain (AOD9604) - Ng et al. (2000) (pubmed)
- Fat oxidation and weight loss research - Heffernan et al. (2001) (article)
- Beta-3 adrenergic receptor mechanism - Heffernan et al. (2001) (article)
- Oral administration lipid effects - Heffernan et al. (2000) (article)
- Osteoarthritis cartilage repair study - Kwon & Park (2015) (pubmed)
- Detection and metabolism study - Cox et al. (2015) (article)
- Antilipogenic action foundational research - Wu & Ng (1993) (pubmed)
- Doxorubicin nanoparticle enhancement - Habibullah et al. (2022) (article)
- 14-kDa hGH fragment angiogenesis inhibition - Shaker et al. (2023) (article)