Cognitive
Dihexa
Dihexa is a synthetic hexapeptide analog of angiotensin IV designed to cross the blood-brain barrier and activate the hepatocyte growth factor (HGF)/c-Met receptor system. It has demonstrated exceptional potency in enhancing synaptic connectivity and cognitive function in animal models, reportedly seven orders of magnitude more potent than BDNF. Research applications focus on neurodegenerative conditions and cognitive enhancement.
Quick Facts
Also known asN-hexanoic-Tyr-Ile-(6) aminohexanoic amide
CategoryCognitive
Half-life6 hours
Routesoral, subcutaneous, intranasal
Common vial sizes10mg, 20mg
Molecular weight507.63 Da
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Cognitive Enhancement | 10 mg | daily | oral | 4 weeks on / 4 weeks off | HGF receptor agonist. 10-20mg daily. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Dihexa Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Dihexa?
Add bacteriostatic water to your Dihexa vial (common sizes: 10mg, 20mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Dihexa?
A common dose for Dihexa is 10 mg daily via oral. HGF receptor agonist. 10-20mg daily.
What is the half-life of Dihexa?
The half-life of Dihexa is approximately 6 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store Dihexa?
Store Dihexa at 2-8°C (refrigerated). Extremely potent compound requiring precise dosing at microgram levels. Handle with appropriate caution. Research chemical only. Once reconstituted, use within 21 days.
Is Dihexa FDA approved?
Dihexa is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
References
- Dihexa Overview (peppedia)
- Dihexa cognitive enhancement in animal models (pubmed)