Anti-Aging / Longevity
Epithalon
Epithalon (epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) based on the natural pineal peptide epithalamin. It has been shown to activate telomerase in human somatic cells, potentially counteracting telomere shortening associated with cellular aging. Research by Professor Khavinson demonstrated that epithalon may modulate melatonin production and neuroendocrine function in aging organisms.
Quick Facts
Also known asEpitalon, Epithalone, AGAG
CategoryAnti-Aging / Longevity
Half-life2 hours
Routessubcutaneous, oral, intranasal
Common vial sizes10mg, 50mg
Molecular weight390.35 Da
Chain length4 amino acids
SequenceAla-Glu-Asp-Gly
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Evidence-Based Longevity | 300 mcg | daily | subcutaneous | 3 weeks on / 17 weeks off | Telomerase activator. |
| Oral Administration | 2 mg | 2x/day | oral | 4 weeks on / 17 weeks off | 2-3 mg twice daily orally. |
| Nasal Spray | 500 mcg | 1-2x/day | intranasal | 3 weeks on / 17 weeks off | 500 mcg - 1 mg intranasally. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Epithalon Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Epithalon?
Add bacteriostatic water to your Epithalon vial (common sizes: 10mg, 50mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Epithalon?
A common dose for Epithalon is 300 mcg daily via subcutaneous. Telomerase activator.
What is the half-life of Epithalon?
The half-life of Epithalon is approximately 2 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store Epithalon?
Store Epithalon at 2-8°C (refrigerated). Short peptide with good stability as lyophilized powder. Protect reconstituted solution from light due to potential melatonin pathway interactions. Once reconstituted, use within 21 days.
Is Epithalon FDA approved?
Epithalon is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
References
- Epithalon Overview (peppedia)
- Epithalon telomerase activation (pubmed)