Hormonal
HGH
Human growth hormone (HGH) is a 191-amino-acid single-chain polypeptide (somatotropin) produced by the anterior pituitary gland. It stimulates linear growth, protein synthesis, lipolysis, and IGF-1 production through activation of the GH receptor/JAK2/STAT5 signaling pathway. Recombinant HGH is FDA-approved for growth hormone deficiency, Turner syndrome, and several other conditions involving impaired growth or body composition.
Quick Facts
Also known asSomatropin, Human Growth Hormone, Somatotropin, rhGH
CategoryHormonal
Half-life3 hours
Routessubcutaneous
Common vial sizes3.33mg, 12mg
Molecular weight22124 Da
Chain length191 amino acids
FDA statusApproved
Storage2-8°C (refrigerated). Reconstituted: 28 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Medical GHD (Starting) | 225 mcg | 1x/day | subcutaneous | Continuous | 0.15-0.3 mg/day (0.5-1 IU) once daily SubQ. Continuous under medical supervision. |
| Medical GHD (Maintenance) | 600 mcg | 1x/day | subcutaneous | Continuous | 0.4-0.8 mg/day (1.2-2.4 IU) once daily SubQ. Continuous under medical supervision. |
| Anti-Aging / Wellness | 500 mcg | 1x/day | subcutaneous | Continuous | 1-2 IU/day (0.33-0.67 mg) once daily SubQ. |
| Body Recomposition | 1 mg | 1-2x/day | subcutaneous | Continuous | 2-4 IU/day (0.67-1.33 mg) once or twice daily SubQ. 3-6 months minimum. |
| Performance (Higher Risk) | 2 mg | 2x/day | subcutaneous | Continuous | 4-8 IU/day (1.33-2.67 mg) split twice daily SubQ. Higher risk of side effects. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your HGH Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute HGH?
Add bacteriostatic water to your HGH vial (common sizes: 3.33mg, 12mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of HGH?
A common dose for HGH is 225 mcg 1x/day via subcutaneous. 0.15-0.3 mg/day (0.5-1 IU) once daily SubQ. Continuous under medical supervision.
What is the half-life of HGH?
The half-life of HGH is approximately 3 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store HGH?
Store HGH at 2-8°C (refrigerated). Prescription pharmaceutical (controlled in many jurisdictions). Do not freeze reconstituted solution. Unreconstituted lyophilized powder can be stored at room temperature for limited periods per manufacturer. Gentle mixing only - do not shake. Once reconstituted, use within 28 days.
Is HGH FDA approved?
Yes, HGH has FDA approval for specific medical indications.
References
- Long-term Safety of Growth Hormone in Adults With Growth Hormone Deficiency (2022) (pubmed)
- Evaluation and Treatment of Adult Growth Hormone Deficiency (2011) (pubmed)
- Long-term efficacy and safety of somatropin for adult growth hormone deficiency (2005) (pubmed)
- The interaction between growth hormone and the thyroid axis (2011) (article)
- Impact of growth hormone treatment on cardiovascular risk factors (2004) (pubmed)
- Adult Growth Hormone Deficiency - Benefits, Side Effects, and Risks (2013) (pubmed)