Healing & Recovery
TB-500
TB-500 is a synthetic fragment of thymosin beta-4, a naturally occurring 43-amino-acid peptide involved in cell migration and tissue repair. It functions primarily by sequestering G-actin monomers and promoting their polymerization, facilitating cellular motility and wound healing. TB-500 has been studied for its role in cardiac repair, dermal wound healing, and corneal tissue regeneration.
Quick Facts
Also known asThymosin Beta-4, TB4
CategoryHealing & Recovery
Half-life2.5 hours
Routessubcutaneous, intramuscular, topical
Common vial sizes2mg, 5mg, 10mg
Molecular weight4963.44 Da
Chain length43 amino acids
SequenceAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| General Tissue Repair | 2.5 mg | 2x/week | subcutaneous | 8 weeks on / 4 weeks off | 2-3 mg twice weekly for tissue repair. |
| Serious Injury Recovery | 5 mg | 3x/week | subcutaneous | 8 weeks on / 4 weeks off | 4-5 mg three times weekly. Inject near injury site. |
| Maintenance | 2 mg | 1-2x/week | subcutaneous | Continuous | Ongoing low-dose maintenance for continued tissue support. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your TB-500 Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute TB-500?
Add bacteriostatic water to your TB-500 vial (common sizes: 2mg, 5mg, 10mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of TB-500?
A common dose for TB-500 is 2.5 mg 2x/week via subcutaneous. 2-3 mg twice weekly for tissue repair.
What is the half-life of TB-500?
The half-life of TB-500 is approximately 2.5 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store TB-500?
Store TB-500 at 2-8°C (refrigerated). Reconstitute with bacteriostatic water. Avoid repeated freeze-thaw cycles. Once reconstituted, use within 21 days.
Is TB-500 FDA approved?
TB-500 is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
Related Calculators
References
- TB-500 Overview (peppedia)
- Thymosin beta-4 promotes tissue repair (pubmed)
- TB-500 healing results (reddit)