Growth Hormone
Tesamorelin
Tesamorelin is an FDA-approved synthetic analog of growth hormone-releasing hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. It stimulates the synthesis and pulsatile release of endogenous growth hormone from the anterior pituitary via the GHRH receptor. Its trans-3-hexenoic acid modification enhances receptor binding affinity and metabolic stability.
Quick Facts
Also known asEgrifta, TH9507
CategoryGrowth Hormone
Half-life26 minutes
Routessubcutaneous
Common vial sizes2mg, 5mg
Molecular weight5135.9 Da
Chain length44 amino acids
SequenceHis-Ala-Asp-Gly-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu
FDA statusApproved
Storage2-8°C (refrigerated). Reconstituted: 14 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Visceral Fat Reduction (FDA-approved) | 2 mg | daily | subcutaneous | Continuous | FDA approved (Egrifta) for HIV lipodystrophy. 15-20% visceral fat reduction. |
| NAFLD Treatment | 2 mg | daily | subcutaneous | 52 weeks | 37% liver fat reduction over 12 months. |
| Cognitive Enhancement | 1 mg | daily | subcutaneous | 20 weeks | 1 mg daily for 20 weeks. GHRH analog stimulating pulsatile GH release. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Tesamorelin Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Tesamorelin?
Add bacteriostatic water to your Tesamorelin vial (common sizes: 2mg, 5mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Tesamorelin?
A common dose for Tesamorelin is 2 mg daily via subcutaneous. FDA approved (Egrifta) for HIV lipodystrophy. 15-20% visceral fat reduction.
What is the half-life of Tesamorelin?
The half-life of Tesamorelin is approximately 26 minutes. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store Tesamorelin?
Store Tesamorelin at 2-8°C (refrigerated). FDA-approved product (Egrifta). Reconstitute immediately before use per manufacturer instructions. Once reconstituted, use within 14 days.
Is Tesamorelin FDA approved?
Yes, Tesamorelin has FDA approval for specific medical indications.
Related Calculators
References
- Tesamorelin Overview (peppedia)
- Tesamorelin visceral fat reduction (pubmed)