Cosmetic
GHK-Cu
GHK-Cu is a naturally occurring copper-binding tripeptide (glycyl-L-histidyl-L-lysine) found in human plasma, saliva, and urine. It stimulates collagen synthesis, glycosaminoglycan production, and promotes wound healing through activation of tissue remodeling pathways. The copper complex also exhibits antioxidant activity and has been widely adopted in cosmetic formulations for skin rejuvenation and hair growth.
Quick Facts
Also known asCopper peptide, Glycyl-L-Histidyl-L-Lysine-Cu2+
CategoryCosmetic
Half-life4 minutes
Routessubcutaneous, topical
Common vial sizes50mg, 100mg, 200mg
Molecular weight404.96 Da
Chain length3 amino acids
SequenceGly-His-Lys
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 30 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Anti-Aging (Injectable) | 1 mg | daily | subcutaneous | 8 weeks on / 8 weeks off | Copper-binding tripeptide. |
| Hair Stimulation (Injectable) | 2 mg | daily | subcutaneous | 8 weeks on / 8 weeks off | 2-3 mg daily. |
| Anti-Aging Skincare (Topical) | 1-2x/day | topical | 16 weeks | 0.5-1% cream. 12-16 week cycles. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your GHK-Cu Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute GHK-Cu?
Add bacteriostatic water to your GHK-Cu vial (common sizes: 50mg, 100mg, 200mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of GHK-Cu?
A common dose for GHK-Cu is 1 mg daily via subcutaneous. Copper-binding tripeptide.
What is the half-life of GHK-Cu?
The half-life of GHK-Cu is approximately 4 minutes. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store GHK-Cu?
Store GHK-Cu at 2-8°C (refrigerated). Copper complex may oxidize upon prolonged light exposure. Store in amber vials when possible. Topical formulations may have different storage requirements. Once reconstituted, use within 30 days.
Is GHK-Cu FDA approved?
GHK-Cu is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
References
- GHK-Cu Overview (peppedia)
- GHK-Cu gene expression effects (pubmed)