Growth Hormone
Ipamorelin
Ipamorelin is a highly selective growth hormone-releasing peptide (GHRP) that acts as a ghrelin mimetic, binding to the growth hormone secretagogue receptor (GHS-R) in the pituitary. Unlike other GHRPs, it does not significantly affect cortisol or prolactin levels at therapeutic doses. It is commonly used in research settings and is often paired with GHRH analogs for synergistic growth hormone release.
Quick Facts
Also known asNNC 26-0161
CategoryGrowth Hormone
Half-life2 hours
Routessubcutaneous
Common vial sizes2mg, 5mg
Molecular weight711.85 Da
Chain length5 amino acids
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| General Health / Sleep | 200 mcg | daily | subcutaneous | 17 weeks on / 9 weeks off | GHRP with minimal cortisol/prolactin impact. Take before bed on empty stomach. |
| Body Composition | 300 mcg | 2x/day | subcutaneous | 17 weeks on / 9 weeks off | 250-300 mcg morning and pre-workout. |
| Anti-Aging Protocol | 250 mcg | 1-2x/day | subcutaneous | 17 weeks on / 9 weeks off | Best combined with CJC-1295 (no DAC) for synergistic GH release. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Ipamorelin Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Ipamorelin?
Add bacteriostatic water to your Ipamorelin vial (common sizes: 2mg, 5mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Ipamorelin?
A common dose for Ipamorelin is 200 mcg daily via subcutaneous. GHRP with minimal cortisol/prolactin impact. Take before bed on empty stomach.
What is the half-life of Ipamorelin?
The half-life of Ipamorelin is approximately 2 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store Ipamorelin?
Store Ipamorelin at 2-8°C (refrigerated). Often combined with CJC-1295 in the same reconstituted solution. Stable as lyophilized powder at room temperature for short periods. Once reconstituted, use within 21 days.
Is Ipamorelin FDA approved?
Ipamorelin is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.
References
- Ipamorelin Overview (peppedia)
- Ipamorelin selective GH release (pubmed)