Growth Hormone
Tesamorelin
Tesamorelin is an FDA-approved synthetic analog of growth hormone-releasing hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. It stimulates the synthesis and pulsatile release of endogenous growth hormone from the anterior pituitary via the GHRH receptor. Its trans-3-hexenoic acid modification enhances receptor binding affinity and metabolic stability.
Quick Facts
Also known asEgrifta, TH9507
CategoryGrowth Hormone
Half-life26 minutes
Routessubcutaneous
Common vial sizes2mg, 5mg
Molecular weight5135.9 Da
Chain length44 amino acids
SequenceHis-Ala-Asp-Gly-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-Gln-Gln-Gly-Glu-Ser-Asn-Gln-Glu-Arg-Gly-Ala-Arg-Ala-Arg-Leu
FDA statusApproved
Storage2-8°C (refrigerated). Reconstituted: 14 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Visceral Fat Reduction (FDA-approved) | 2 mg | daily | subcutaneous | Continuous | FDA approved (Egrifta) for HIV lipodystrophy. 15-20% visceral fat reduction. |
| NAFLD Treatment | 2 mg | daily | subcutaneous | 52 weeks | 37% liver fat reduction over 12 months. |
| Cognitive Enhancement | 1 mg | daily | subcutaneous | 20 weeks | 1 mg daily for 20 weeks. GHRH analog stimulating pulsatile GH release. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Tesamorelin Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Tesamorelin?
Add bacteriostatic water to your Tesamorelin vial (common sizes: 2mg, 5mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Tesamorelin?
A common dose for Tesamorelin is 2 mg daily via subcutaneous. FDA approved (Egrifta) for HIV lipodystrophy. 15-20% visceral fat reduction.
What is the half-life of Tesamorelin?
The half-life of Tesamorelin is approximately 26 minutes. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store Tesamorelin?
Store Tesamorelin at 2-8°C (refrigerated). FDA-approved product (Egrifta). Reconstitute immediately before use per manufacturer instructions. Once reconstituted, use within 14 days.
Is Tesamorelin FDA approved?
Yes, Tesamorelin has FDA approval for specific medical indications.
References
- Tesamorelin Overview (peppedia)
- Tesamorelin visceral fat reduction (pubmed)