Cognitive
NA Semax Amidate
NA-Semax-Amidate is an enhanced derivative of Semax featuring N-acetyl and C-terminal amide modifications that increase lipophilicity, blood-brain barrier penetration, and resistance to enzymatic degradation. These structural changes result in greater potency and duration of action compared to unmodified Semax. It retains the neurotrophic, neuroprotective, and cognitive-enhancing properties of the parent compound with improved pharmacokinetic characteristics.
Quick Facts
Also known asN-Acetyl Semax Amidate, Enhanced Semax, Modified Semax
CategoryCognitive
Half-life2 hours
Routesintranasal, subcutaneous
Molecular weight1007.16 Da
Chain length7 amino acids
SequenceAsn-Ala-Met-Glu-His-Phe-Pro-Gly-Pro-NH2
FDA statusNot approved
Storage2-8°C (refrigerated). Reconstituted: 21 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Cognitive Enhancement | 600 mcg | 1x/day | intranasal | 4 weeks | 600 mcg intranasal spray, 2-3 drops per nostril, 10-30 day cycles. |
| Mental Fatigue Resistance | 800 mcg | 1x/day | intranasal | 4 weeks | 800 mcg intranasal spray once daily. |
| Memory Enhancement | 600 mcg | 2x/day | intranasal | 4 weeks | 600 mcg 2x daily intranasal spray. |
| Neuroprotection | 1.2 mg | 1x/day | intranasal | 4 weeks | 1200 mcg intranasal spray once daily. |
| Research Protocol (SubQ) | 200 mcg | 1x/day | subcutaneous | 3 weeks | 200 mcg once daily SubQ, 7-21 day cycles. |
| Neuroprotection Study (SubQ) | 400 mcg | 1x/day | subcutaneous | 3 weeks | 400 mcg once daily SubQ. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
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Start Tracking — FreeCommon Questions
What is the typical dose of NA Semax Amidate?
A common dose for NA Semax Amidate is 600 mcg 1x/day via intranasal. 600 mcg intranasal spray, 2-3 drops per nostril, 10-30 day cycles.
What is the half-life of NA Semax Amidate?
The half-life of NA Semax Amidate is approximately 2 hours. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store NA Semax Amidate?
Store NA Semax Amidate at 2-8°C (refrigerated). Intranasal administration preferred for CNS bioavailability. More stable than unmodified Semax due to terminal modifications. Store nasal solutions refrigerated. Once reconstituted, use within 21 days.
Is NA Semax Amidate FDA approved?
NA Semax Amidate is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.