Cognitive
Pinealon
Pinealon is a synthetic tripeptide (Glu-Asp-Arg) developed as a pineal gland bioregulator within the Khavinson peptide framework. It is reported to normalize melatonin production and circadian rhythm function by modulating gene expression in pinealocytes. Research has explored its neuroprotective properties and potential to improve sleep quality and cognitive function in aging populations.
Quick Facts
Also known asEDR, Glu-Asp-Arg
CategoryCognitive
Routessubcutaneous, oral
Common vial sizes2mg, 3mg, 5mg, 10mg
Molecular weight418.4 Da
Chain length3 amino acids
SequenceGlu-Asp-Arg
FDA statusNot approved
StorageRoom temperature (15-25°C). Reconstituted: 90 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Neuroprotection | 5 mg | 1x/day | subcutaneous | 3 weeks on / 9 weeks off | 5mg daily subcutaneous. Clinical protocol showed significant cognitive improvements in 72-patient study. |
| Cognitive Enhancement (Injectable) | 200 mcg | 1x/day or every other day | subcutaneous | 4 weeks on / 9 weeks off | 100-300mcg range. Functions through direct gene expression modulation and MAPK/ERK pathway. |
| Anti-Aging | 5 mg | 1x/day | subcutaneous | 3 weeks on / 17 weeks off | 5mg daily for 20 days, repeated 2-3x yearly. |
| Oral Cognitive Enhancement | 200 mcg | 2x/day | oral | 4 weeks on / 9 weeks off | 0.2mg twice daily oral. Post-TBI trial showed improved memory and reduced headache severity in 72 patients. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your Pinealon Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute Pinealon?
Add bacteriostatic water to your Pinealon vial (common sizes: 2mg, 3mg, 5mg, 10mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of Pinealon?
A common dose for Pinealon is 5 mg 1x/day via subcutaneous. 5mg daily subcutaneous. Clinical protocol showed significant cognitive improvements in 72-patient study.
How should I store Pinealon?
Store Pinealon at Room temperature (15-25°C). Short bioregulatory tripeptide typically available in capsule form. Store in a cool, dry place. Oral bioavailability reported for short peptides in this class. Once reconstituted, use within 90 days.
Is Pinealon FDA approved?
Pinealon is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.