Growth Hormone
IGF-1 LR3
IGF-1 LR3 is an 83-amino-acid analog of insulin-like growth factor-1 featuring an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. These modifications dramatically reduce binding to IGF-binding proteins, resulting in a significantly extended half-life and greater bioavailability compared to native IGF-1. It potently activates the IGF-1 receptor to promote cellular proliferation, differentiation, and inhibition of apoptosis.
Quick Facts
Also known asLong R3 IGF-1, IGF-1 Long Arg3
CategoryGrowth Hormone
Half-life~1 day
Routessubcutaneous, intramuscular
Common vial sizes2mg, 3mg, 5mg, 10mg
Chain length83 amino acids
FDA statusNot approved
Storage-20°C (frozen). Reconstituted: 14 days.
Dosing Protocols
| Goal | Dose | Frequency | Route | Cycle | Notes |
|---|---|---|---|---|---|
| Beginner | 25 mcg | 1x/day | subcutaneous | 5 weeks on / 5 weeks off | 20-30 mcg once daily post-workout. 4-6 weeks max, equal off period required. |
| Intermediate | 50 mcg | 1x/day | subcutaneous | 5 weeks on / 5 weeks off | 40-60 mcg once daily SubQ/IM. 4-6 weeks max, equal off period required. |
| Advanced | 90 mcg | 1x/day | subcutaneous | 5 weeks on / 5 weeks off | 80-100 mcg once daily or split AM/PM SubQ/IM. 4-6 weeks max. |
| Women's Protocol | 15 mcg | 1x/day | subcutaneous | 5 weeks on / 5 weeks off | 10-20 mcg once daily SubQ only. 4-6 weeks max. |
Protocols shown are for informational purposes only. Consult a healthcare provider before starting any peptide protocol.
Track Your IGF-1 LR3 Protocol
Log doses, manage vial inventory, set injection reminders, and visualize blood concentration levels.
Start Tracking — FreeCommon Questions
How do I reconstitute IGF-1 LR3?
Add bacteriostatic water to your IGF-1 LR3 vial (common sizes: 2mg, 3mg, 5mg, 10mg). The amount of BAC water depends on your desired concentration. Use our reconstitution calculator for exact measurements.
What is the typical dose of IGF-1 LR3?
A common dose for IGF-1 LR3 is 25 mcg 1x/day via subcutaneous. 20-30 mcg once daily post-workout. 4-6 weeks max, equal off period required.
What is the half-life of IGF-1 LR3?
The half-life of IGF-1 LR3 is approximately ~1 day. This determines how long the peptide remains active in your body and influences dosing frequency.
How should I store IGF-1 LR3?
Store IGF-1 LR3 at -20°C (frozen). Potent growth factor requiring precise microgram-level dosing. Store lyophilized at -20°C. Reconstitute with acetic acid solution (0.6% recommended), not bacteriostatic water. Avoid repeated freeze-thaw of reconstituted aliquots. Once reconstituted, use within 14 days.
Is IGF-1 LR3 FDA approved?
IGF-1 LR3 is not FDA approved and is available for research purposes only. It has not been evaluated by the FDA for safety or efficacy in humans.